GHK CU Lysyl oxidase like 2 Encyclopedia MDPI Lysine Hydroxylation and Cross Linking of Collagen Springer Nature Link How GHK Peptide Works Signaling GHK acts as a switch for skin repair: Interacts with adenosine receptors reduces inflammation Activates MAPK ERK, PI3K Akt, TGF pathways Stimulates fibroblasts & keratinocytes boosts collagen, elastin File:Tropocollagen cross linkage lysyl oxidase (EN).svg Wikimedia Commons Developing functional musculoskeletal tissues through hypoxia and lysyl oxidase induced collagen cross linking PNAS