Multifaceted Roles of Glutathione and Glutathione Based Systems in Carcinogenesis and Anticancer Drug Resistance Elie Hatem, Nadine El Banna, Meng Er Huang, 2017 Full article: Inhibiting system xC and glutathione biosynthesis a potential Achilles' heel in mutant p53 cancers Targeting the Vulnerability of Glutathione Metabolism in ARID1A Deficient Cancers: Cancer Cell NRF2 supports non small cell lung cancer growth independently of CBP p300 enhanced glutathione synthesis EMBO Reports Springer Nature Link Mitochondrial glutathione import identified as key driver of breast cancer spread Mitochondrial glutathione, imported via the SLC25A39 transporter, is essential for breast cancer metastasis, particularly during early colonization of new tissues. Elevated Role of GSH in carcinogenesis . Glutathione has been shown to regulate Download Scientific Diagram