Frontiers The Role of the Pentose Phosphate Pathway in Diabetes and Cancer Glucose metabolism begins with its transport into cells via GLUT transporters, where it is phosphorylated to glucose 6 phosphate (Glucose 6 P). This molecule can enter various pathways, including the pentose phosphate pathway or hexosamine biosynthesis. Pentose Phosphate Pathway Hexose Monophosphate Pathway Metabolism Glutathione Pathways pentose phosphate pathway in biology: Definition, Types and Importance AESL The Pentose Phosphate Pathway (HMP shunt) & G6PD deficiency (Favism)