DNA Replication in Animal Systems Lacking Thioredoxin Reductase I IntechOpen Frontiers Assigning function to active site residues of Schistosoma mansoni thioredoxin glutathione reductase from analysis of transient state reductive half reactions with variant forms of the enzyme Molecular Medicine Reports Structure and mechanism of mammalian thioredoxin reductase: The active site is a redox active selenolthiol selenenylsulfide formed from the conserved cysteine selenocysteine sequence PNAS Known components of the thioredoxin system (top) and glutaredoxin Download Scientific Diagram Evolutionarily Conserved Role of Thioredoxin Systems in Determining Longevity