Small molecule activation of the neurotrophin hepatocyte growth factor to treat Alzheimer disease Dihexa (also known as PNB 0408) is an experimental small molecule derived from angiotensin IV. It was engineered to cross the bloodbrain barrier and has shown synaptogenic effects in preclinical models. The often quoted HGF c Met pathway facilitates the perineural invasion of pancreatic cancer by activating the mTOR NGF axis Cell Death & Disease Anti cancer therapeutic strategies based on HGF MET, EpCAM, and tumor stromal cross talk Cancer Cell International Springer Nature Link Schematic representation of pathway interactions among HGF c Met, Download Scientific Diagram Peptide Comparisons Blog Peptide Protocol Wiki Peptide Protocol Wiki