Glutathione in cancer progression and chemoresistance: an update in: Redox Experimental Medicine Volume 2023 Issue 1 (2023) Amplification of TP63 in human squamous cell lung cancer upregulates Download Scientific Diagram A study from the Birsoy lab showed that the antioxidant glutathione, when operating inside mitochondria, is a key factor enabling tumors to spread from the breast to the lung. #RockefellerScience #YearInReview A non canonical function of LDHB promotes SLC7A11 mediated glutathione metabolism and protects against glutaminolysis dependent ferroptosis in KRAS driven lung cancer bioRxiv New research targeting senescent zombie" cells highlights potential #cancer therapies reducing inflammation, tumor growth, and treatment related damage through Glutathione Peroxidase 4 (GPX4) inhibition. . Article Decreased glutathione biosynthesis contributes to EGFR T790M driven erlotinib resistance in non small cell lung cancer Cell Discovery