Frontiers Research progress of glutathione peroxidase family (GPX) in redoxidation GPX1 (Glutathione Peroxidase, GSHPx) Gene Variants and Cardiovascular Revolution Health & Wellness TJ. Glutathione peroxidase is an important enzyme in cellular antioxidant defense systems, detoxifying peroxides and hydroperoxides. As a component of the glutathione cycle, it protects the liver from reactive oxygen metabolites. Selenocysteine AZD5904 Glutathione Peroxidase 2 an overview ScienceDirect Topics Non covalent interactions in the glutathione peroxidase active center and their influence on the enzyme activity Organic & Biomolecular Chemistry (RSC Publishing)