The broccoli derivative sulforaphane extends lifespan by slowing the transcriptional aging clock bioRxiv 11 Best Sulforaphane Rich Foods (With Tasty Recipes to Try!) Hitchcock Farms What Is Glutathione? A Summary of Glutathione Lifespan Research Institute Glucoraphanin Antioxidant MedChemExpress Yes there is good evidence that acetaminophen (the active ingredient in Tylenol) can deplete glutathione under certain conditions. But whether that matters depends on dose, duration, and individual factors. Acetaminophen and NSAID Toxicity Life Extension