Oral Melanoma: A Rare but Aggressive Oral Cancer Oral melanoma is a rare and highly aggressive malignant tumor that develops from melanocytes within the oral mucosa. It most commonly affects the Is focal melanotic lesion potentially malignant? A case report ScienceDirect ORAL MELANOTIC MACULE (OMM) (Also called focal melanosis labial melanotic macule) A benign, localized, flat pigmented lesion of the oral mucosa Caused by a focal increase in melanin production Pigmented Lesions Springer Nature Link Pathology Outlines Melanotic macule Pigmented Lesions Springer Nature Link