Understanding the Impact of Acetaminophen: Tylenol and Glutathione in Autism Psychopharmacology Debates: Tylenol or NSAIDs? Heres why you should avoid Tylenol , First of all, it is full of colorful dyes, sugars, and additives., But the main reason is it depletes glutathione., Glutathione is one of the most Acetaminophen metabolism Parents ask me this all the time: Motrin or Tylenol for fever? Here's my pediatric naturopathic perspective: Motrin treats inflammation, which often drives fever It lasts longer, so fewer doses Acetaminophen Toxicity Poisoning