Oral Melanotic Macule MEDizzy Pigmentation on the oral mucosa, hands, and feet European Journal of Internal Medicine Brown spots, especially on the lips, can be alarming to some. In some instances it can indicate rare oral mucosal melanoma, however in this case it was a non cancerous labial melanotic macule. Pigmented Lesions of the Oral Mucosa Pocket Dentistry What to do with pigmented oral lesions? Congenital Melanocytic Macule of the Tongue in a Newborn Cureus