Smoking and vaping don't affect your eligibility to donate. Become a donor and give life today. Can You Donate Blood If You Smoke? Cannabis, Nicotine, and More Is Vaping Safe? It Can Cause Higher Risk of Heart Attack, According to a New Study. Cone Health We all know smoking and vaping isn't great for your health. But it doesn't stop you from being a blood or plasma donor. Just make sure to wait one hour after donating Just How Harmful Is Vaping? More Evidence Is Emerging. The New York Times you can chose vaping or a nicotine pouch, what do you choose?